Directorio

Hernández-Vázquez, E.*, Estrada-Soto, S.*, Lumbreras-Zavala, N., Mundo-Campuzano, M., Chávez-Silva, F., Villalobos-Molina, R., & Hernández-Luis, F. (2022). Enhancing the antidiabetic and antidyslipidemic activity of a 1,5-diarylpyrazole by solid dispersion pre-formulation. Chemical Papers, 76(9), 5551-5560.
DOI:10.1007/s11696-022-02260-7

Martínez-Ortega, U., Figueroa-Figueroa, D. I., Hernández-Luis, F., & Aguayo-Ortiz, R. (2021). In Silico Characterization of Masitinib Interaction with SARS-CoV-2 Main Protease. ChemMedChem.
DOI:10.1002/cmdc.202100375

Mendoza-Martinez, C., Rodriguez-Lezama, A., Galindo-Sevilla, N., Cortés-Guzmán, F., Hernandez-Pineda, J., Nieto-Lara, A., & Hernandez-Luis, F. (2020). Impact of Conformations and Size on the Antileishmanial Activity of New Quinazoline Derivatives. ChemRxiv.
DOI:10.26434/chemrxiv.12746915.v1

Herrera-Vázquez, F. S., Matadamas-Martínez, F., Aguayo-Ortiz, R., Dominguez, L., Ramírez-Apan, T., Yépez-Mulia, L., & Hernández-Luis, F. (2020). Design, Synthesis and Evaluation of 2,4‐Diaminoquinazoline Derivatives as Potential Tubulin Polymerization Inhibitors. ChemMedChem, 15(19), 1802-1812.
DOI:10.1002/cmdc.202000185

Santos-Cruz, L. F., Ramírez-Cruz, B. G., García-Salomé, M., Olvera-Romero, Z. Y., Hernández-Luis, F., Hernández-Portilla, L. B., Durán-Díaz, Á., Dueñas-García, I. E., Castañeda-Partida, L., Piedra-Ibarra, E., Mendoza-Martínez, C., & Heres-Pulido, M. E. (2020). Genotoxicity assessment of four novel quinazoline-derived trypanocidal agents in the Drosophila wing somatic mutation and recombination test. Mutagenesis, 35(4), 299-310.
DOI:10.1093/mutage/gez042

González-Hernández, I., Palomares-Alonso, F., Becerril-Vega, J., De La Torre, S. M., Hernández-Luis, F., Rodriguez-Morales, S., Aguayo-Ortiz, R., Dominguez, L., Rodríguez-Balderas, C. A., González-Maciel, A., Rojas-Tomé, I. S., Castro, N., & Jung-Cook, H. (2019). Evaluation of new benzimidazole derivatives as cysticidal agents: In vitro, in vivo and docking studies. Chemical and Pharmaceutical Bulletin, 67(12), 1293-1300.
DOI:10.1248/cpb.c19-00574

Santos-Cruz, L. F., Ramírez-Cruz, B. G., García-Salomé, M., Olvera-Romero, Z. Y., Hernández-Luis, F., Hernández-Portilla, L. B., Durán-Díaz, A., Dueñas-García, I. E., Castañeda-Partida, L., Piedra-Ibarra, E., Mendoza-Martínez, C., & Heres-Pulido, M. E. (2019). Genotoxicity assessment of four novel quinazoline-derived trypanocidal agents in the Drosophila wing somatic mutation and recombination test. Mutagenesis.
DOI:10.1093/mutage/gez042

Herrera-Vázquez, F. S., Hernández-Luis, F., & Medina Franco, J. L. (2019). Quinazolines as inhibitors of chromatin-associated proteins in histones. Medicinal Chemistry Research, 28(4), 395-416.
DOI:10.1007/s00044-019-02300-0

Matus-Meza, A. S., Velasco-Velázquez, M. A., & Hernández-Luis, F. (2018). Design, synthesis and cytotoxic evaluation of quinazoline-2,4,6-triamine and 2,6-diaminoquinazolin-4(3H)-one derivatives. Medicinal Chemistry Research, 27(7), 1748-1756, ISSN: 1554-8120.
DOI:10.1007/s00044-018-2188-7

Sánchez-Salgado, J. C., Bilbao-Ramos, P., Dea-Ayuela, M. A., Hernández-Luis, F., Bolás-Fernández, F., Medina-Franco, J. L., & Rojas-Aguirre, Y. (2018). Systematic search for benzimidazole compounds and derivatives with antileishmanial effects. Molecular Diversity, 22(4), 779-790.
DOI:10.1007/s11030-018-9830-7

Melchor-Doncel de la Torre, S., Vázquez, C., González-Chávez, Z., Yépez-Mulia, L., Nieto-Meneses, R., Jasso-Chávez, R., Saavedra, E., & Hernández-Luis, F. (2017). Synthesis and biological evaluation of 2-methyl-1H-benzimidazole-5-carbohydrazides derivatives as modifiers of redox homeostasis of trypanosoma cruzi. Bioorganic and Medicinal Chemistry Letters, 27(15), 3403-3407.
DOI:10.1016/j.bmcl.2017.06.013

Vázquez-Raygoza, A., Cano-González, L., Velázquez-Martínez, I., Trejo-Soto, P. J., Castillo, R., Hernández-Campos, A., Hernández-Luis, F., Oria-Hernández, J., Castillo-Villanueva, A., Avitia-Domínguez, C., Sierra-Campos, E., Valdez-Solana, M., & Téllez-Valencia, A. (2017). Species-specific inactivation of triosephosphate isomerase from trypanosoma brucei: Kinetic and molecular dynamics studies. Molecules, 22(12).
DOI:10.3390/molecules22122055

Herrera-Pérez, J. J., Martínez-Mota, L., Jiménez-Rubio, G., Ortiz-López, L., Cabrera-Muñoz, E. A., Galindo-Sevilla, N., Zambrano, E., Hernández-Luis, F., Ramírez-Rodríguez, G. B., & Flores-Ramos, M. (2017). Dehydroepiandrosterone increases the number and dendrite maturation of doublecortin cells in the dentate gyrus of middle age male wistar rats exposed to chronic mild stress. Behavioural Brain Research, 321, 137-147.
DOI:10.1016/j.bbr.2017.01.007

Hernández-Vázquez, E., Salgado-Barrera, S., Ramírez-Espinosa, J. J., Estrada-Soto, S., & Hernández-Luis, F. (2016). Synthesis and molecular docking of N′-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents. Bioorganic and Medicinal Chemistry, 24(10), 2298-2306.
DOI:10.1016/j.bmc.2016.04.007

Mendoza-Martínez, C., Galindo-Sevilla, N., Correa-Basurto, J., Ugalde-Saldivar, V. M., Rodriguez-Delgado, R. G., Hernández-Pineda, J., Padierna-Mota, C., Flores-Alamo, M., & Hernandez-Luis, F. (2015). Antileishmanial activity of quinazoline derivatives: Synthesis, docking screens, molecular dynamic simulations and electrochemical studies. European Journal of Medicinal Chemistry, 92, 314-331, ISSN: 0223-5234.
DOI:10.1016/j.ejmech.2014.12.051

Rojas-Aguirre, Y., Castillo, I., Hernández, D. J., Nogueda-Torres, B., Márquez-Navarro, A., Villalobos, J. C., Sánchez-Bartéz, F., Sánchez-Torres, L., Gracia-Mora, I., Castillo, R., & Hernández-Luis, F. (2012). Diversity in the supramolecular interactions of 5,6-dichloro-2- (trifluoromethyl)-1H-benzimidazole with modified cyclodextrins: Implications for physicochemical properties and antiparasitic activity. Carbohydrate Polymers, 87(1), 471-479, ISSN: 0144-8617.
DOI:10.1016/j.carbpol.2011.08.009