María Josefa Bernad Bernad

Departamento: Farmacia
   Perfil: Profesores-Investigadores
 Nombramiento: Profesor de Carrera Titular
   Ubicación: Edificio F1, Cubículo 001, planta baja, Facultad de Química
  Teléfono: 55 56223849

 
 
Grados académicos
 
 

Licenciada en Farmacia.
Doctora en Ciencias Químicas.


Docencia en Licenciatura y Posgrado
 
 

[L] Tecnología Farmacéutica II
[L] Fisicoquímica Farmacéutica
[L] Sistemas estímulo sensibles I y II


Áreas de investigación
 
 
  • Teragnosticos
  • Liberación modificada de fármacos
  • Vectorización
  • Permeabilidad
  • Nanotecnología farmacéutica

Línea de Investigación
 
 
  • Diseño, desarrollo y caracterización de nuevos sistemas de liberación de fármacos y teragnósticos
  • Nanopartículas como estrategia de permeación a través de mucosas
    Nanogeles estímulo sensibles como modo de vetorización de principios activos

Su investigación está dirigida al diseño, elaboración y caracterización de sistemas inteligentes de cesión de fármacos y/o diagnóstico; en particular sistemas coloidales que logren control temporal, direccionalidad y liberación bajo estímulos externos o internos.


Posgrados en los que participa
 
 
  • Ciencias Químicas, Posgrado en Salud y Producción animal, Medicina, UAM Xochimilco (Ciencias Farmacéuticas)
  • Materiales, Ingeniería, Facultad de Farmacia (UAEM)

Premios y distinciones
 
 
  • Premio Canifarma 1998
  • Premio Canifarma 2007
  • Premio Canifarma Veterinaria 2008
  • Candidata SNI desde 2001 a 2006
  • SNI nivel 1 desde enero 2007

Publicaciones recientes
 
 

Rojas-Montoya, I. D., Fosado-Esquivel, P., Henao-Holguín, L. V., Ramírez-Rave, S., Bernad-Bernad, M., & Gracia-Mora, J. (2020). Hydroxyapatite nanoparticles synthesized via reverse microemulsions and their adsorption/desorption properties with enrofloxacin. Journal of Crystal Growth, 549.
DOI:10.1016/j.jcrysgro.2020.125878

Rojas-Montoya, I. D., Fosado-Esquivel, P., Henao-Holguín, L. V., Esperanza-Villegas, A. E., Bernad-Bernad, M. J., & Gracia-Mora, J. (2020). Adsorption/desorption studies of norfloxacin on brushite nanoparticles from reverse microemulsions. Adsorption, 26(6), 825-834.
DOI:10.1007/s10450-019-00138-x

Resendiz, A. S., Bernad Bernad, M. J., Sanchez Lemus, J. C., Rodríguez, I. J., Carlin Valderrabano, S. C., & Estrada, D. V. (2020). Disposition and pharmacokinetics of azithromycin in serum and a lung tissue of two modified-release formulations compared with an immediate-release product on the market. Pakistan Journal of Pharmaceutical Sciences, 33(3), 1079-1085.

Pineda-Álvarez, R. A., Bernad-Bernad, M. J., Rodríguez-Cruz, I. M., & Escobar-Chávez, J. J. (2020). Development and Characterization of Starch/Gelatin Microneedle Arrays Loaded with Lecithin–Gelatin Nanoparticles of Losartan for Transdermal Delivery. Journal of Pharmaceutical Innovation.
DOI:10.1007/s12247-020-09494-6

Ramírez-Rave, S., Bernad-Bernad, M. J., Gracia-Mora, J., & Yatsimirsky, A. K. (2020). Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus. Mini-Reviews in Medicinal Chemistry, 20(11), 1001-1016.
DOI:10.2174/1389557519666190904145355

Carrillo, L., Bernad, M. -., Monroy-Barreto, M., Coello, C. L., Sumano, H., & Gutiérrez, L. (2020). Higher Bioavailability of Calcium in Chickens With a Novel In-Feed Pharmaceutical Formulation. Frontiers in Veterinary Science, 7.
DOI:10.3389/fvets.2020.00343

Arciniegas, S. M., Saavedra, S. A., Balderas, D., del Carmen Caballero, S., Bernad, M. J., Sánchez, J. C., Gracia, M. I., Rico, H. A., & Vargas, D. (2020). Comparison in the Glucose Response of Flexible Liposomes Loaded with Insulin with the Addition of Different Surfactants in an Experimental Diabetes Model. Letters in Drug Design and Discovery, 17(6), 795-806.
DOI:10.2174/1570180816666191024102231

Ceja‐Medina, L. I., Ortiz‐Basurto, R. I., Medina‐Torres, L., Calderas, F., Bernad‐Bernad, M. J., González‐Laredo, R. F., Ragazzo-Sánchez, J. A., Calderón-Santoyo, M., González-Ávila, M., Andrade-González, I., & Manero, O. (2020). Microencapsulation of Lactobacillus plantarum by spray drying with mixtures of Aloe vera mucilage and agave fructans as wall materials. Journal of Food Process Engineering.
DOI:10.1111/jfpe.13436

Henao-Holguin, L. V., Cornejo-Santiago, E., Rojas-Montoya, I. D., Gracia-Mora, J., & Bernad-Bernad, M. J. (2020). MWCNT-riboflavin nanocomposite for collagen crosslinking: A green approach. Materials Chemistry and Physics, 241.
DOI:10.1016/j.matchemphys.2019.122361

Orona-Ortiz, A., Medina-Torres, L., Velázquez-Moyado, J. A., Pineda-Peña, E. A., Balderas-López, J. L., Bernad-Bernad, M. J., Tavares Carvalho, J. C., & Navarrete, A. (2019). Mucoadhesive effect of curcuma longa extract and curcumin decreases the ranitidine effect, but not bismuth subsalicylate on ethanol-induced ulcer model. Scientific Reports, 9(1).
DOI:10.1038/s41598-019-53089-2

Gutierrez, L., Mendoza, J., Rangel, A. B., Tapia, G., Bernad, M. J., & Sumano, H. (2019). Outpatient clinical trial in dogs with leptospirosis treated with enrofloxacin hydrochloride-dihydrate (ENRO-C). Frontiers in Veterinary Science, 6.
DOI:10.3389/fvets.2019.00360

García-Guzmán, P., Medina-Torres, L., Calderas, F., Bernad-Bernad, M. J., Gracia-Mora, J., Marcos, X., Correa-Basurto, J., Núñez-Ramírez, D.M., & Manero, O. (2019). Rheological mucoadhesion and cytotoxicity of montmorillonite clay mineral/hybrid microparticles biocomposite. Applied Clay Science, 180.
DOI:10.1016/j.clay.2019.105202

Medina-Torres, L., Núñez-Ramírez, D. M., Calderas, F., González-Laredo, R. F., Minjares-Fuentes, R., Valadez-García, M. A., Bernad-Bernad, M.J., & Manero, O. (2019). Microencapsulation of gallic acid by spray drying with aloe vera mucilage (aloe barbadensis miller) as wall material. Industrial Crops and Products, 138.
DOI:10.1016/j.indcrop.2019.06.024

Medina-Torres, L., Núñez-Ramírez, D. M., Calderas, F., Bernad-Bernad, M. J., Gracia-Mora, J., Rodríguez-Ramírez, J., González-Laredo, R.F., Gallegos-Infante, J.A., & Manero, O. (2019). Curcumin encapsulation by spray drying using aloe vera mucilage as encapsulating agent. Journal of Food Process Engineering, 42(2).
DOI:10.1111/jfpe.12972

Rojas-Montoya, I. D., Fosado-Esquivel, P., Henao-Holguín, L. V., Esperanza-Villegas, A. E., Bernad-Bernad, M. J., & Gracia-Mora, J. (2019). Adsorption/desorption studies of norfloxacin on brushite nanoparticles from reverse microemulsions. Adsorption.
DOI:10.1007/s10450-019-00138-x

Estrada-San Agustín, E., Gutiérrez, L., Bernad, M., Castillo-Juárez, H., Sánchez, S., & Sumano, H. (2019). Pharmacokinetics of two dosing forms of a recrystallized enrofloxacin as hydrochloride dihydrate in tilapia (oreochromis niloticus × oreochromis mossambicus). Aquaculture International, 27(3), 849-857.
DOI:10.1007/s10499-019-00371-9

Arciniegas, S. M., Bernad, M. J., Caballero, S. C., Hernandez, D., Solis, B., & Vargas, A. D. (2019). Process for physicochemical improvement of ultra-flexible liposomes loaded with insulin. Indian Journal of Pharmaceutical Sciences, 81(1), 110-116.
DOI:10.4172/pharmaceutical-sciences.1000485

Arciniegas, S. M., Bernad, M. J., Carlin, S. C., Juárez, I., & Vargas, D. (2019). Long-acting oral formulation of doxycycline: In vitroin vivo correlation studies. Indian Journal of Pharmaceutical Sciences, 81(4), 608-617.
DOI:10.36468/pharmaceutical-sciences.551

Aquino, I., Gutiérrez-Blanco, E., Ocampo, L., Gutiérrez, L., Bernad-Bernad, M. J., & Sumano, H. (2019). Anesthetic evaluation of a novel phospholipid-free 1% propofol microemulsion formulation in dogs. Veterinaria Mexico, 6(3).
DOI:10.22201/fmvz.24486760e.2019.3.654

Ramírez-Rave, S., Bernad-Bernad, M., Gracia-Mora, J.*, & Yatsimirsky, A.* (2019). Recent Advances in Application of Azobenzenes Grafted on Mesoporous Silica Nanoparticles in Controlled Drug Delivery Systems Using Light as External Stimulus. Mini-Reviews in Medicinal Chemistry, 19.
DOI:10.2174/1389557519666190904145355

Marcos, X., Padilla-Beltrán, C., Bernad-Bernad, M. J., Rosales-Hernández, M. C., Pérez-Casas, S., & Correa-Basurto, J. (2018). Controlled release of N-(2-hydroxyphenyl)-2-propylpentanamide nanoencapsulated in polymeric micelles of P123 and F127 tested as anti-proliferative agents in MDA-MB-231 cells. Journal of Drug Delivery Science and Technology, 48, 403-413.
DOI:10.1016/j.jddst.2018.10.005

Miranda-Calderón, J. E., Macías-Rosales, L., Gracia-Mora, I., Ruiz-Azuara, L., Faustino-Vega, A., Gracia-Mora, J., & Bernad-Bernad, M. J. (2018). Effect of casiopein III-ia loaded into chitosan nanoparticles on tumor growth inhibition. Journal of Drug Delivery Science and Technology, 48, 1-8.
DOI:10.1016/j.jddst.2018.07.004

García-Guzmán, P., Medina-Torres, L., Calderas, F., Bernad-Bernad, M. J., Gracia-Mora, J., Mena, B., & Manero, O. (2018). Characterization of hybrid microparticles/Montmorillonite composite with raspberry-like morphology for atorvastatin controlled release. Colloids and Surfaces B: Biointerfaces, 167, 397-406.
DOI:10.1016/j.colsurfb.2018.04.020

Gutierrez, L., Alcala, Y., Bernad, M. J., & Sumano, H. (2018). Increased bioavailability of tylosin phosphate as in-feed medication formulated for long-action pellets in broiler chickens. Journal of Applied Poultry Research, 27(1), 16-22.
DOI:10.3382/japr/pfx035

Medina-Torres, L., Calderas, F., Nuñez Ramírez, D. M., Herrera-Valencia, E. E., Bernad Bernad, M. J., & Manero, O. (2017). Spray drying egg using either maltodextrin or nopal mucilage as stabilizer agents. Journal of Food Science and Technology, 54(13), 4427-4435.
DOI:10.1007/s13197-017-2919-7

Pérez-Salinas, P., Jaramillo-Soto, G., Rosas-Aburto, A., Vázquez-Torres, H., Bernad-Bernad, M. J., Licea-Claverie, Á., & Vivaldo-Lima, E. (2017). Comparison of polymer networks synthesized by conventional free radical and RAFT copolymerization processes in supercritical carbon dioxide. Processes, 5(2).
DOI:10.3390/pr5020026

Ortega, E., Gutiérrez, L., Bernad, M. J., Salmerón, F., Juárez, I., & Vargas, D. (2017). Evaluation of different oral formulations of clindamycin extended release in dogs. Drug Research, 67(1), 32-37.
DOI:10.1055/s-0042-115637

Medina-Torres, L., Santiago-Adame, R., Calderas, F., Gallegos-Infante, J. A., González-Laredo, R. F., Rocha-Guzmán, N. E., Núñez-Ramírez, D. M., Bernad-Bernad, M. J., & Manero, O. (2016). Microencapsulation by spray drying of laurel infusions (litsea glaucescens) with maltodextrin. Industrial Crops and Products, 90, 1-8.
DOI:10.1016/j.indcrop.2016.06.009

Calderas, F., Medina-Torres, L., Linares-Alba, M. A., Urbano-López, H. E., Bernad-Bernad, M. J., & Manero, O. (2016). Rheology of the ultrasound-induced gelation in poloxamer aqueous solutions. Rheologica Acta, 55(10), 781-787.
DOI:10.1007/s00397-016-0953-4

Vega, A. F., Medina-Torres, L., Calderas, F., Gracia-Mora, J., & Bernad-Bernad, M. (2016). Closantel nano-encapsulated polyvinyl alcohol (PVA) solutions. Pharmaceutical Development and Technology, 21(5), 636-641.
DOI:10.3109/10837450.2015.1035725

Linares-Alba, M. A., Gómez-Guajardo, M. B., Fonzar, J. F., Brooks, D. E., García-Sánchez, G. A., & Bernad-Bernad, M. J. (2016). Preformulation studies of a liposomal formulation containing sirolimus for the treatment of dry eye disease. Journal of Ocular Pharmacology and Therapeutics, 32(1), 11-22.
DOI:10.1089/jop.2015.0032

Última actualización: 1º de febrero de 2021